Ontology highlight
ABSTRACT:
SUBMITTER: Escher D
PROVIDER: S-EPMC7756626 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Escher Daniela D Müller Jens J
Chemistry (Weinheim an der Bergstrasse, Germany) 20201029 68
DNA duplexes comprising 6-(1H-pyrazol-1-yl)-9H-purine (6PP), 1-deaza-6PP (<sup>1D</sup> 6PP), 7-deaza-6PP (<sup>7D</sup> 6PP) and 1,7-dideaza-6PP (<sup>1,7D</sup> 6PP) 2'-deoxyribonucleosides, respectively, were investigated towards their ability to form metal-mediated base pairs in the presence of Ag<sup>I</sup> . In 6PP and <sup>7D</sup> 6PP, the Ag<sup>I</sup> ion can coordinate to the nucleobase via the endocyclic N1 nitrogen atom, that is, via the Watson-Crick edge. In contrast, this nitrog ...[more]