Ontology highlight
ABSTRACT:
SUBMITTER: Kuiper-Makris C
PROVIDER: S-EPMC7769986 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Scientific reports 20201228 1
Intrauterine growth restriction (IUGR) and low birth weigth (LBW) are risk factors for neonatal chronic lung disease. However, maternal and fetal genetic factors and the molecular mechanisms remain unclear. We investigated the relationship between LBW and lung function with Mendelian randomisation analyses and studied angiogenesis in a low protein diet rat model of IUGR. Our data indicate a possible association between LBW and reduced FEV1 (p = 5.69E-18, MR-PRESSO) and FVC (6.02E-22, MR-PRESSO). ...[more]