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Novel therapies for acromegaly.


ABSTRACT: Acromegaly is a systemic disease associated with increased morbidity and mortality. Most of these comorbidities can be prevented or delayed with adequate disease treatment. Although three modalities of treatment (surgery, medical treatment, and radiotherapy) are available and new drugs were approved in the last decades, there are still some patients that maintain disease activity despite treatment. Therefore, there is a need for novel therapies for acromegaly and for that purpose new formulations of currently used drugs and also new drugs are currently under study. In this review, we summarize the novel therapies for acromegaly.

SUBMITTER: Maia B 

PROVIDER: S-EPMC7774757 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

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Novel therapies for acromegaly.

Maia Bernardo B   Kasuki Leandro L   Gadelha Mônica R MR  

Endocrine connections 20201201 12


Acromegaly is a systemic disease associated with increased morbidity and mortality. Most of these comorbidities can be prevented or delayed with adequate disease treatment. Although three modalities of treatment (surgery, medical treatment, and radiotherapy) are available and new drugs were approved in the last decades, there are still some patients that maintain disease activity despite treatment. Therefore, there is a need for novel therapies for acromegaly and for that purpose new formulation  ...[more]

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