Ontology highlight
ABSTRACT:
SUBMITTER: Wang J
PROVIDER: S-EPMC7781082 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Leukemia & lymphoma 20190122 6
DNA methylation (DNAm) silences gene expression and may play a role in immune dysregulation that is characteristic of adolescent/young adult Hodgkin lymphoma (AYAHL). We used the Infinium HumanMethylation27 BeadChip to quantify DNAm in blood (<i>N</i> = 9 pairs, mean age 57.4 y) or saliva (<i>N</i> = 36 pairs, mean age 50.0 y) from long-term AYAHL survivors and their unaffected co-twins. Epigenetic aging (DNAm age) was calculated using previously described methods and compared between survivors ...[more]