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Crystallographic and spectroscopic characterization of 3-chloro-5-fluoro-salicyl-aldehyde.

ABSTRACT: The title compound (systematic name: 3-chloro-5-fluoro-2-hy-droxy-benzaldehyde), C₇H₄ClFO₂, is a dihalogenated salicyl-aldehyde derivative that has been studied for its anti-bacterial characteristics. The salicyl-aldehyde engages in intra-molecular hydrogen bonding with an O-H?O distance of 2.6231?(19)?Å while the mol-ecules pack together via weak inter-molecular C-H?O, C-H?F and F?O inter-actions and offset face-to-face ?-stacking.

SUBMITTER: Triggs CT

PROVIDER: S-EPMC7784655 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

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Crystallographic and spectroscopic characterization of 3-chloro-5-fluoro-salicyl-aldehyde.

Triggs Christopher T CT Tanski Joseph M JM

Acta crystallographica. Section E, Crystallographic communications 20201103 Pt 12

The title compound (systematic name: 3-chloro-5-fluoro-2-hy-droxy-benzaldehyde), C7H4ClFO2, is a dihalogenated salicyl-aldehyde derivative that has been studied for its anti-bacterial characteristics. The salicyl-aldehyde engages in intra-molecular hydrogen bonding with an O-H⋯O distance of 2.6231 (19) Å while the mol-ecules pack together via weak inter-molecular C-H⋯O, C-H⋯F and F⋯O inter-actions and offset face-to-face π-stacking. ...[more]

PMID: 33520258

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