Ontology highlight
ABSTRACT:
SUBMITTER: Nascimento C
PROVIDER: S-EPMC7795286 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Nascimento Catarina C Gameiro Andreia A Ferreira João J Correia Jorge J Ferreira Fernando F
Cancers 20210101 1
Vascular endothelial growth factor (VEGF-A) plays an essential role in tumor-associated angiogenesis, exerting its biological activity by binding and activating membrane receptors, as vascular endothelial growth factor receptor 1 and 2 (VEGFR-1, VEGFR-2). In this study, serum VEGF-A, VEGFR-1, and VEGFR-2 levels were quantified in 50 cats with mammary carcinoma and 14 healthy controls. The expression of these molecules in tumor-infiltrating lymphocytes (TILs) and in cancer cells was evaluated and ...[more]