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A case report on transient cardiomyopathy with cytokine storm in SARS-CoV-2.

ABSTRACT:

Background

Cardiac manifestations during Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) pandemic have included acute coronary syndrome, arrhythmias, myocarditis, and stress cardiomyopathy. However, the combination of cardiomyopathy and negative cardiac biomarkers has not yet been reported.

Case summary

A 49-year-old man admitted for respiratory failure secondary to SARS-CoV-2 developed new-onset cardiomyopathy with negative cardiac biomarkers. Left ventricular ejection fraction and strain improved 7 days after the initial echocardiogram, after administration of Tocilizumab, coinciding with clinical recovery, and improvement in inflammatory markers.

Discussion

As experience of cardiovascular manifestations of SARS-CoV-2 increases, more patients will likely present with cardiovascular manifestations; the recognition and proper management of these may improve patient outcomes.

SUBMITTER: Tarun T

PROVIDER: S-EPMC7799318 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature

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A case report on transient cardiomyopathy with cytokine storm in SARS-CoV-2.

Tarun Tushar T Kumar Senthil S Johnson Jeremy J Chockalingam Anand A

European heart journal. Case reports 20201229 2

<h4>Background</h4>Cardiac manifestations during Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) pandemic have included acute coronary syndrome, arrhythmias, myocarditis, and stress cardiomyopathy. However, the combination of cardiomyopathy and negative cardiac biomarkers has not yet been reported.<h4>Case summary</h4>A 49-year-old man admitted for respiratory failure secondary to SARS-CoV-2 developed new-onset cardiomyopathy with negative cardiac biomarkers. Left ventricular eject ...[more]

PMID: 33594344

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