Ontology highlight
ABSTRACT:
SUBMITTER: Hjortbak MV
PROVIDER: S-EPMC7801421 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Scientific reports 20210111 1
A multitargeted strategy to treat the consequences of ischemia and reperfusion (IR) injury in acute myocardial infarction may add cardioprotection beyond reperfusion therapy alone. We investigated the cardioprotective effect of mild hypothermia combined with local ischemic preconditioning (IPC) or remote ischemic conditioning (RIC) on IR injury in isolated rat hearts. Moreover, we aimed to define the optimum timing of initiating hypothermia and evaluate underlying cardioprotective mechanisms. Co ...[more]