Ontology highlight
ABSTRACT:
SUBMITTER: Mayne B
PROVIDER: S-EPMC7803548 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Mayne Benjamin B Korbie Darren D Kenchington Lisa L Ezzy Ben B Berry Oliver O Jarman Simon S
Aging 20201223 24
Changes in DNA methylation at specific CpG sites have been used to build predictive models to estimate animal age, predominantly in mammals. Little testing for this effect has been conducted in other vertebrate groups, such as bony fish, the largest vertebrate class. The development of most age-predictive models has relied on a genome-wide sequencing method to obtain a DNA methylation level, which makes it costly to deploy as an assay to estimate age in many samples. Here, we have generated a re ...[more]