Ontology highlight
ABSTRACT:
SUBMITTER: van Hooij A
PROVIDER: S-EPMC7807156 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
iScience 20201229 1
To end the decade-long, obstinately stagnant number of new leprosy cases, there is an urgent need for field-applicable diagnostic tools that detect infection with <i>Mycobacterium leprae</i>, leprosy's etiologic agent. Since immunity against <i>M. leprae</i> is characterized by humoral and cellular markers, we developed a lateral flow test measuring multiple host proteins based on six previously identified biomarkers for various leprosy phenotypes. This multi-biomarker test (MBT) demonstrated fe ...[more]