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Facile preparation and conversion of 4,4,4-trifluorobut-2-yn-1-ones to aromatic and heteroaromatic compounds.


ABSTRACT: The concise preparation of 4,4,4-trifluorobut-2-yn-1-ones by the oxidation of the readily accessible corresponding propargylic alcohols as well as their utilization as Michael acceptors for the construction of aromatic and heteroaromatic compounds are reported.

SUBMITTER: Yamazaki T 

PROVIDER: S-EPMC7814177 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature

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Facile preparation and conversion of 4,4,4-trifluorobut-2-yn-1-ones to aromatic and heteroaromatic compounds.

Yamazaki Takashi T   Nakajima Yoh Y   Iida Minato M   Kawasaki-Takasuka Tomoko T  

Beilstein journal of organic chemistry 20210115


The concise preparation of 4,4,4-trifluorobut-2-yn-1-ones by the oxidation of the readily accessible corresponding propargylic alcohols as well as their utilization as Michael acceptors for the construction of aromatic and heteroaromatic compounds are reported. ...[more]

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