Ontology highlight
ABSTRACT:
SUBMITTER: Suh BK
PROVIDER: S-EPMC7814725 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Suh Bo Kyoung BK Lee Seol-Ae SA Park Cana C Suh Yeongjun Y Kim Soo Jeong SJ Woo Youngsik Y Nhung Truong Thi My TTM Lee Su Been SB Mun Dong Jin DJ Goo Bon Seong BS Choi Hyun Sun HS Kim So Jung SJ Park Sang Ki SK
Molecular brain 20210118 1
Mitochondrial movement in neurons is finely regulated to meet the local demand for energy and calcium buffering. Elaborate transport machinery including motor complexes is required to deliver and localize mitochondria to appropriate positions. Defects in mitochondrial transport are associated with various neurological disorders without a detailed mechanistic information. In this study, we present evidence that dystrobrevin-binding protein 1 (dysbindin), a schizophrenia-associated factor, plays a ...[more]