Ontology highlight
ABSTRACT:
SUBMITTER: Pleyer C
PROVIDER: S-EPMC7820878 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Pleyer Christopher C Ali Mir A MA Cohen Jeffrey I JI Tian Xin X Soto Susan S Ahn Inhye E IE Gaglione Erika M EM Nierman Pia P Marti Gerald E GE Hesdorffer Charles C Lotter Jennifer J Superata Jeanine J Wiestner Adrian A Sun Clare C
Blood 20210101 2
Vaccinations are effective in preventing infections; however, it is unknown if patients with chronic lymphocytic leukemia (CLL) who are treatment naïve (TN) or receiving Bruton tyrosine kinase inhibitors (BTKi's) respond to novel adjuvanted vaccines. Understanding the effect of BTKi's on humoral immunity is timely because BTKi's are widely used and vaccination against coronavirus disease 2019 is urgently needed. In 2 open-label, single-arm clinical trials, we measured the effect of BTKi's on de ...[more]