Ontology highlight
ABSTRACT:
SUBMITTER: Fiore PF
PROVIDER: S-EPMC7826641 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Fiore Piera Filomena PF Vacca Paola P Tumino Nicola N Besi Francesca F Pelosi Andrea A Munari Enrico E Marconi Marcella M Caruana Ignazio I Pistoia Vito V Moretta Lorenzo L Azzarone Bruno B
Cancers 20210109 2
The immune response plays a crucial defensive role in cancer growth and metastasis and is a promising target in different tumors. The role of the immune system in Wilm's Tumor (WT), a common pediatric renal malignancy, is still to be explored. The characterization of the immune environment in WT could allow the identification of new therapeutic strategies for targeting possible inhibitory mechanisms and/or lowering toxicity of the current treatments. In this study, we stabilized four WT primary ...[more]