Ontology highlight
ABSTRACT:
SUBMITTER: Park C
PROVIDER: S-EPMC7834019 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Park Chanhyun C Sakurai Yuki Y Sato Hirofumi H Kanda Shinji S Iino Yuichi Y Kunitomo Hirofumi H
eLife 20210125
The ability of animals to process dynamic sensory information facilitates foraging in an ever-changing environment. However, molecular and neural mechanisms underlying such ability remain elusive. The ClC anion channels/transporters play a pivotal role in cellular ion homeostasis across all phyla. Here, we find a ClC chloride channel is involved in salt concentration chemotaxis of <i>Caenorhabditis elegans</i>. Genetic screening identified two altered-function mutations of <i>clh-1</i> that disr ...[more]