Ontology highlight
ABSTRACT:
SUBMITTER: Kang YF
PROVIDER: S-EPMC7839421 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Kang Yin-Feng YF Sun Cong C Zhuang Zhen Z Yuan Run-Yu RY Zheng Qingbing Q Li Jiang-Ping JP Zhou Ping-Ping PP Chen Xin-Chun XC Liu Zhe Z Zhang Xiao X Yu Xiao-Hui XH Kong Xiang-Wei XW Zhu Qian-Ying QY Zhong Qian Q Xu Miao M Zhong Nan-Shan NS Zeng Yi-Xin YX Feng Guo-Kai GK Ke Changwen C Zhao Jin-Cun JC Zeng Mu-Sheng MS
ACS nano 20210119 2
The coronavirus disease pandemic of 2019 (COVID-19) caused by the novel SARS-CoV-2 coronavirus resulted in economic losses and threatened human health worldwide. The pandemic highlights an urgent need for a stable, easily produced, and effective vaccine. SARS-CoV-2 uses the spike protein receptor-binding domain (RBD) to bind its cognate receptor, angiotensin-converting enzyme 2 (ACE2), and initiate membrane fusion. Thus, the RBD is an ideal target for vaccine development. In this study, we desig ...[more]