Central aortic hemodynamics following acute lower and upper-body exercise in a cold environment among patients with coronary artery disease.

ABSTRACT: Exercise is beneficial to cardiovascular health, evidenced by reduced post-exercise central aortic blood pressure (BP) and wave reflection. We assessed if post-exercise central hemodynamics are modified due to an altered thermal state related to exercise in the cold in patients with coronary artery disease (CAD). CAD patients (n?=?11) performed moderate-intensity lower-body exercise (walking at 65-70% of HR_max) and rested in neutral (+?22 °C) and cold (-?15 °C) conditions. In another protocol, CAD patients (n?=?15) performed static (five 1.5 min work cycles, 10-30% of maximal voluntary contraction) and dynamic (three 5 min workloads, 56-80% of HR_max) upper-body exercise at the same temperatures. Both datasets consisted of four 30-min exposures administered in random order. Central aortic BP and augmentation index (AI) were noninvasively assessed via pulse wave analyses prior to and 25 min after these interventions. Lower-body dynamic exercise decreased post-exercise central systolic BP (6-10 mmHg, p?

SUBMITTER: Hintsala HE 

PROVIDER: S-EPMC7843633 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature