Ontology highlight
ABSTRACT:
SUBMITTER: Ponomarev SA
PROVIDER: S-EPMC7849230 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Beilstein journal of organic chemistry 20210127
The Diels-Alder reaction of β-fluoro-β-nitrostyrenes with cyclic 1,3-dienes was investigated. A series of novel monofluorinated norbornenes was prepared in up to 97% yield. The reaction with 1,3-cyclohexadiene permits the preparation of monofluorinated bicyclo[2.2.2]oct-2-enes. The kinetic data of the reactions with 1,3-cyclopentadiene and 1,3-cyclohexadiene were used to calculate activation parameters. Furthermore, the synthetic utility of the cycloadducts obtained was demonstrated. ...[more]