Ontology highlight
ABSTRACT:
SUBMITTER: Dondelinger F
PROVIDER: S-EPMC7868060 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Dondelinger Frank F Mukherjee Sach S
Biostatistics (Oxford, England) 20200401 2
We consider high-dimensional regression over subgroups of observations. Our work is motivated by biomedical problems, where subsets of samples, representing for example disease subtypes, may differ with respect to underlying regression models. In the high-dimensional setting, estimating a different model for each subgroup is challenging due to limited sample sizes. Focusing on the case in which subgroup-specific models may be expected to be similar but not necessarily identical, we treat subgrou ...[more]