Ontology highlight
ABSTRACT:
SUBMITTER: Burton CL
PROVIDER: S-EPMC7870035 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Burton Christie L CL Lemire Mathieu M Xiao Bowei B Corfield Elizabeth C EC Erdman Lauren L Bralten Janita J Poelmans Geert G Yu Dongmei D Shaheen S-M SM Goodale Tara T Sinopoli Vanessa M VM Soreni Noam N Hanna Gregory L GL Fitzgerald Kate D KD Rosenberg David D Nestadt Gerald G Paterson Andrew D AD Strug Lisa J LJ Schachar Russell J RJ Crosbie Jennifer J Arnold Paul D PD
Translational psychiatry 20210202 1
Using a novel trait-based measure, we examined genetic variants associated with obsessive-compulsive (OC) traits and tested whether OC traits and obsessive-compulsive disorder (OCD) shared genetic risk. We conducted a genome-wide association analysis (GWAS) of OC traits using the Toronto Obsessive-Compulsive Scale (TOCS) in 5018 unrelated Caucasian children and adolescents from the community (Spit for Science sample). We tested the hypothesis that genetic variants associated with OC traits from ...[more]