Ontology highlight
ABSTRACT:
SUBMITTER: Ottenheimer DJ
PROVIDER: S-EPMC7870109 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Nature neuroscience 20200810 10
The nervous system is hypothesized to compute reward prediction errors (RPEs) to promote adaptive behavior. Correlates of RPEs have been observed in the midbrain dopamine system, but the extent to which RPE signals exist in other reward-processing regions is less well understood. In the present study, we quantified outcome history-based RPE signals in the ventral pallidum (VP), a basal ganglia region functionally linked to reward-seeking behavior. We trained rats to respond to reward-predicting ...[more]