Ontology highlight
ABSTRACT:
SUBMITTER: Edmans M
PROVIDER: S-EPMC7884753 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Edmans Matthew M McNee Adam A Porter Emily E Vatzia Eleni E Paudyal Basu B Martini Veronica V Gubbins Simon S Francis Ore O Harley Ross R Thomas Amy A Burt Rachel R Morgan Sophie S Fuller Anna A Sewell Andrew A Charleston Bryan B Bailey Mick M Tchilian Elma E
Frontiers in immunology 20210202
We have used the pig, a large natural host animal for influenza with many physiological similarities to humans, to characterize αβ, γδ T cell and antibody (Ab) immune responses to the 2009 pandemic H1N1 virus infection. We evaluated the kinetic of virus infection and associated response in inbred Babraham pigs with identical MHC (Swine Leucocyte Antigen) and compared them to commercial outbred animals. High level of nasal virus shedding continued up to days 4 to 5 post infection followed by a st ...[more]