Ontology highlight
ABSTRACT:
SUBMITTER: Park HW
PROVIDER: S-EPMC7907745 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Park Hyun Woo HW Song Min Seok MS Sim Hun Ju HJ Ryu Pan Dong PD Lee So Yeong SY
BMB reports 20210201 2
Voltage-gated potassium (Kv) channels are involved in many important cellular functions and play pivotal roles in cancer progression. The expression level of Kv2.1 was observed to be higher in the highly metastatic prostate cancer cells (PC-3), specifically in their membrane, than in immortalized prostate cells (WPMY-1 cells) and comparatively less metastatic prostate cancer cells (LNCaP and DU145 cells). However, Kv2.1 expression was significantly decreased when the cells were treated with anti ...[more]