Ontology highlight
ABSTRACT:
SUBMITTER: Ciccone L
PROVIDER: S-EPMC7911533 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Ciccone Lidia L Vandooren Jennifer J Nencetti Susanna S Orlandini Elisabetta E
Pharmaceuticals (Basel, Switzerland) 20210124 2
Several studies have reported neuroprotective effects by natural products. A wide range of natural compounds have been investigated, and some of these may play a beneficial role in Alzheimer's disease (AD) progression. Matrix metalloproteinases (MMPs), a family of zinc-dependent endopeptidases, have been implicated in AD. In particular, MMP-2 and MMP-9 are able to trigger several neuroinflammatory and neurodegenerative pathways. In this review, we summarize and discuss existing literature on nat ...[more]