Dataset Information
3D Structural Insights into ?-Glucans and Their Binding Proteins.
Ontology highlight
ABSTRACT:
SUBMITTER: Manabe N
PROVIDER: S-EPMC7915573 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Publications
3D Structural Insights into β-Glucans and Their Binding Proteins.
International journal of molecular sciences 20210204 4
β(1,3)-glucans are a component of fungal and plant cell walls. The β-glucan of pathogens is recognized as a non-self-component in the host defense system. Long β-glucan chains are capable of forming a triple helix structure, and the tertiary structure may profoundly affect the interaction with β-glucan-binding proteins. Although the atomic details of β-glucan binding and signaling of cognate receptors remain mostly unclear, X-ray crystallography and NMR analyses have revealed some aspects of β-g ...[more]