Ontology highlight
ABSTRACT:
SUBMITTER: McGrowder DA
PROVIDER: S-EPMC7916561 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
McGrowder Donovan A DA Miller Fabian F Vaz Kurt K Nwokocha Chukwuemeka C Wilson-Clarke Cameil C Anderson-Cross Melisa M Brown Jabari J Anderson-Jackson Lennox L Williams Lowen L Latore Lyndon L Thompson Rory R Alexander-Lindo Ruby R
Brain sciences 20210210 2
Alzheimer's disease is a progressive, clinically heterogeneous, and particularly complex neurodegenerative disease characterized by a decline in cognition. Over the last two decades, there has been significant growth in the investigation of cerebrospinal fluid (CSF) biomarkers for Alzheimer's disease. This review presents current evidence from many clinical neurochemical studies, with findings that attest to the efficacy of existing core CSF biomarkers such as total tau, phosphorylated tau, and ...[more]