Ontology highlight
ABSTRACT:
SUBMITTER: Oliveira RKM
PROVIDER: S-EPMC7917787 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Oliveira Rayssa Karla de Medeiros RKM Hurtado Fabián Andrés FA Gomes Pedro Henrique PH Puglia Luiza Lassi LL Ferreira Fernanda Fonsêca FF Ranjan Kunal K Albuquerque Patrícia P Poças-Fonseca Márcio José MJ Silva-Pereira Ildinete I Fernandes Larissa L
Journal of fungi (Basel, Switzerland) 20210212 2
Pathogenic microbes are exposed to a number of potential DNA-damaging stimuli during interaction with the host immune system. Microbial survival in this situation depends on a fine balance between the maintenance of DNA integrity and the adaptability provided by mutations. In this study, we investigated the association of the DNA repair response with the virulence of <i>Cryptococcus neoformans</i>, a basidiomycete that causes life-threatening meningoencephalitis in immunocompromised individuals. ...[more]