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Catalytic Enantioselective Synthesis of ?-Allenyl Boronic Esters by Conjunctive Cross-Coupling with Propargylic Carbonates.

ABSTRACT: Enantioselective conjunctive cross-coupling with propargylic carbonates affords (?-boryl allenes as the reaction product. The reaction is found to proceed through the intermediacy of dimethoxyboronate complexes that are generated in situ by a strain-induced ligand exchange reaction.

SUBMITTER: Aparece MD

PROVIDER: S-EPMC7943035 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

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Catalytic Enantioselective Synthesis of β-Allenyl Boronic Esters by Conjunctive Cross-Coupling with Propargylic Carbonates.

Aparece Mark D MD Hu Weipeng W Morken James P JP

ACS catalysis 20191031 12

Enantioselective conjunctive cross-coupling with propargylic carbonates affords (β-boryl allenes as the reaction product. The reaction is found to proceed through the intermediacy of dimethoxyboronate complexes that are generated in situ by a strain-induced ligand exchange reaction. ...[more]

PMID: 33692912

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