Association of Infant Physical Development and Rapid Growth With Pubertal Onset Among Girls in Rural China.

ABSTRACT:

Importance

Whether physical development and rapid growth during the first 2 years of life are associated with puberty onset in girls remains unclear.

Objective

To examine the associations of infant physical development and rapid growth with the timing of puberty onset in girls.

Design, setting, and participants

This prospective birth cohort study included girls whose mothers had participated in a randomized, double-blind cluster trial of micronutrient supplementation with a daily capsule of folic acid, iron and folic acid, or multiple micronutrients during pregnancy. A total of 547 singleton girls in rural western China who were born after 2004 were followed up at 3, 6, 12, and 24 months of age and were eligible for long-term follow-up. Of these, 294 adolescent girls

SUBMITTER: Wei J 

PROVIDER: S-EPMC8094009 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature