Regional Diets Targeting Gut Microbial Dynamics to Support Prolonged Healthspan.

ABSTRACT: In the last 150 years, we have seen a significant increase in average life expectancy, associated with a shift from infectious to non-communicable diseases. The rising incidence of these diseases, for which age is often the largest risk factor, highlights the need for contemporary societies to improve healthy ageing for their growing silver generations. As ageing is an inevitable, non-reversing and highly individualised process, we need to better understand how non-genetic factors like diet choices and commensal gut microbes can modulate the biology of ageing. In this review, we discuss how geographical and ethnic variations influence habitual dietary patterns, nutrient structure, and gut microbial profiles with potential impact on the human healthspan. Several gut microbial genera have be

SUBMITTER: Low DY 

PROVIDER: S-EPMC8116520 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature