Three-Component Reactions of 3-Arylidene-3H-Indolium Salts, Isocyanides and Amines.
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ABSTRACT: A multicomponent reaction of isocyanides with aryl(indol-3-yl)methylium salts and amines has been found. A series of aryl(indol-3-yl)acetimidamides was obtained in up to 96% yields. In the case of ethyl isocyanoacetate, the reaction is followed by cyclization to form 3,5-dihydro-4H-imidazol-4-one derivatives.
SUBMITTER: Nguyen HM
PROVIDER: S-EPMC8122609 | biostudies-literature |
REPOSITORIES: biostudies-literature
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