A protein interactions map of multiple organ systems associated with COVID-19 disease.

ABSTRACT: Coronavirus disease 2019 (COVID-19) is an on-going pandemic disease infecting millions of people across the globe. Recent reports of reduction in antibody levels and the re-emergence of the disease in recovered patients necessitated the understanding of the pandemic at the core level. The cases of multiple organ failures emphasized the consideration of different organ systems while managing the disease. The present study employed RNA sequencing data to determine the disease associated differentially regulated genes and their related protein interactions in several organ systems. It signified the importance of early diagnosis and treatment of the disease. A map of protein interactions of multiple organ systems was built and uncovered CAV1 and CTNNB1 as the top degree nodes. A core interacti

SUBMITTER: Bharne D 

PROVIDER: S-EPMC8261268 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature