An in silico drug repositioning workflow for host-based antivirals.
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ABSTRACT:
SUBMITTER: Li Z
PROVIDER: S-EPMC8273420 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Publications
An <i>in silico</i> drug repositioning workflow for host-based antivirals.
Li Zexu Z Yao Yingjia Y Cheng Xiaolong X Li Wei W Fei Teng T
STAR protocols 20210707 3
Drug repositioning represents a cost- and time-efficient strategy for drug development. Artificial intelligence-based algorithms have been applied in drug repositioning by predicting drug-target interactions in an efficient and high throughput manner. Here, we present a workflow of <i>in silico</i> drug repositioning for host-based antivirals using specially defined targets, a refined list of drug candidates, and an easily implemented computational framework. The workflow described here can also ...[more]
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