Surface-Grafted Poly(ionic liquid) that Lubricates in Both Non-polar and Polar Solvents.
Ontology highlight
ABSTRACT:
SUBMITTER: Burgess D
PROVIDER: S-EPMC8296680 | biostudies-literature |
REPOSITORIES: biostudies-literature
Similar Datasets
Project description:The less polar phase of liquid-liquid extraction systems has been studied extensively for improving metal separations; however, the role of the more polar phase has been overlooked for far too long. Herein, we investigate the extraction of metals from a variety of polar solvents and demonstrate that, the influence of polar solvents on metal extraction is so significant that extraction of many metals can be largely tuned, and the metal separations can be significantly enhanced by selecting suitable polar solvents. Furthermore, a mechanism on how the polar solvents affect metal extraction is proposed based on comprehensive characterizations. The method of using suitable polar solvents in liquid-liquid extraction paves a new and versatile way to enhance metal separations.
| S-EPMC6771523 | biostudies-literature
Project description:Non-polar solvents like hexane allow ionization of insoluble drugs, peptides, nucleotides and phospholipids as solids from paper. Ambient ionization is achieved simply by application of a high voltage to the wet paper. Transport and ionization mechanisms are discussed, including the possibility of field desorption from dendritic structures formed on the paper.
| S-EPMC3591489 | biostudies-literature
Project description:Background: Biofilm infection caused by multidrug-resistant bacteria is difficult to eradicate by conventional therapies. Photodynamic therapy (PDT) is an effective antibacterial method for fighting against biofilm infection. However, the blocked photosensitizers outside of biofilm greatly limit the efficacy of PDT. Methods: Herein, a novel acid-responsive superporogen and photosensitizer (SiO2-PCe6-IL) was developed. Because of the protonation of the photosensitizer and the high binding energy of the polyionic liquid, SiO2-PCe6-IL changed to positive SiO2-PIL + in an acidic microenvironment of biofilm infection. SiO2-PIL + could combine with negatively charged extracellular polymeric substances (EPS) and create holes to remove the biofilm barrier. To strengthen the interaction between SiO2-PIL + and EPS, SiO2-PIL + of high charge density was prepared by grafting the high-density initiation site of ATRP onto the surface of the SiO2 base. Results: Due to the rapid protonation rate of COO- and the strong binding energy of SiO2-PIL + with EPS, SiO2-PCe6-IL could release 90% of Ce6 in 10 s. With the stronger electrostatic and hydrophobic interaction of SiO2-PIL + with EPS, the surface potential, hydrophobicity, adhesion and mechanical strength of biofilm were changed, and holes in the biofilm were created in 10 min. Combining with the release of photosensitizers and the porous structure of the biofilm, Ce6 was efficiently concentrated in the biofilm. The in vitro and in vivo antibacterial experiments proved that SiO2-PCe6-IL dramatically improved the PDT efficacy against MRSA biofilm infection. Conclusion: These findings suggest that SiO2-PCe6-IL could rapidly increase the concentration of photosensitizer in biofilm and it is an effective therapy for combating biofilm infection.
| S-EPMC7163436 | biostudies-literature
Project description:Polymer-based nanoparticles have an increasing presence in research due to their attractive properties, such as flexible surface functionality design and the ability to scale up production. Poly(ionic liquid) (PIL) nanoparticles of size below 50 nm are very unique in terms of their high charge density and internal onion-like morphology. The interaction between PIL nanoparticles and giant unilamellar vesicles (GUVs) of various surface charge densities is investigated. GUVs represent a convenient model system as they mimic the size and curvature of plasma membranes, while simultaneously offering direct visualization of the membrane response under the microscope. Incubating PIL nanoparticles with GUVs results in poration of the lipid membrane in a concentration- and charge-dependent manner. A critical poration concentration of PILs is located and the interactions are found to be analogous to those of antimicrobial peptides. Microbial mimetic membranes are already affected at submicromolar PIL concentrations where contrast loss is observed due to sugar exchange across the membrane, while at high concentrations the collapse of vesicles is observed. Finally, a confocal microscopy-based approach assessing the particle permeation through the membrane is reported and a mechanism based on bilayer frustration and pore stabilization via particle integration in the membrane is proposed.
| S-EPMC6382306 | biostudies-literature
Project description:Wounds, particularly under low-hydration conditions, require more time to repair successfully. Therefore, there is an urgent need to develop wound dressings that can accelerate wound healing. Hydrogels, which can maintain a moist environment around the wound and allow gas to pass through the material, act as antibacterial hydrogels as dressings and have great application value in the treatment of wounds. In addition, wound dressings (hydrogels) containing antibacterial capacity have lasting antibacterial effects and reduce damage to cells. In this work, we firstly synthesized two antibacterial agents: imidazolium poly(ionic liquids) containing sulfhydryl (Imidazole-SH) and ε-Poly(lysine) containing SH (EPL-SH). Then, lysine as a cross-linking agent, by "thiol-ene" click reaction, was mixed with Deferoxamine (DFO) to prepare the antibacterial hydrogels. The in vitro assays showed that the hydrogels could effectively kill Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus). In addition, it also could reduce the inflammatory response produced by Lipopolysaccharide (LPS). More importantly, according to the transwell and angiogenesis assays, DFO-incorporated hydrogels promoted the migration and vascular repair of human umbilical vein endothelial cells (HUVECs). All the results revealed that the hydrogels provided new strategies for wound dressings.
| S-EPMC9407512 | biostudies-literature
Project description:This study presents the large scale computer simulations of two common fluorophores, N-methyl-6-oxyquinolinium betaine and coumarin 153, in five polar or ionic solvents. The validity of linear response approximations to calculate the time-dependent Stokes shift is evaluated in each system. In most studied systems linear response theory fails. In ionic liquids the magnitude of the overall response is largely overestimated, and linear response theory is not able to capture the individual contributions of cations and anions. In polar liquids, the timescales of solvation dynamics are often not correctly reproduced. These observations are complemented by a detailed analysis of Gaussian statistics including higher order correlation functions, variance of the energy gap distribution and its time evolution. The analysis of higher order correlation functions was found to be not suitable to predict a failure of linear response theory. Further analysis of radial distribution functions and hydrogen bonds in the ground and excited state, as well as the time evolution of the number of hydrogen bonds after solute excitation reveal an influence of solvent structure in some of the studied systems.
| S-EPMC5815284 | biostudies-literature
Project description:Solution-based processing of two-dimensional (2D) nanomaterials is highly desirable, especially for the low-temperature large-area fabrication of flexible multifunctional devices. MXenes, an emerging family of 2D materials composed of transition metal carbides, carbonitrides, or nitrides, provide excellent electrical and electrochemical properties through aqueous processing. Here, we further expand the horizon of MXene processing by introducing a polymeric superdispersant for MXene nanosheets. Segmented anchor-spacer structures of a comb-type polymer, polycarboxylate ether (PCE), provide polymer grafting-like steric spacings over the van der Waals range of MXene surfaces, thereby reducing the colloidal interactions by the order of 103, regardless of solvent. An unprecedented broad dispersibility window for Ti3C2Tx MXene, covering polar, nonpolar, and even ionic solvents, was achieved. Furthermore, close PCE entanglements in MXene@PCE composite films resulted in highly robust properties upon prolonged mechanical and humidity stresses.
| S-EPMC8967220 | biostudies-literature
Project description:A brush type nanomotor was fabricated via assembly assistant polymerization of poly(ionic liquid) and surface grafting polymerization. The method for large-scale fabrication of brush nanomotors with soft surfaces is described. These soft locomotive particles are based on core-shell brush nanoparticles assembled from poly(ionic liquid) as core and thermoresponsive PNIPAM as brush shells on which platinum nanoparticle (PtNP) were grown in situ. The particles show non-Brownian motion in H?O? solution.
| S-EPMC6082249 | biostudies-literature
Project description:We present here the possibility of forming triphilic mixtures from alkyl- and fluoroalkylimidazolium ionic liquids, thus, macroscopically homogeneous mixtures for which instead of the often observed two domains-polar and nonpolar-three stable microphases are present: polar, lipophilic, and fluorous ones. The fluorinated side chains of the cations indeed self-associate and form domains that are segregated from those of the polar and alkyl domains. To enable miscibility, despite the generally preferred macroscopic separation between fluorous and alkyl moieties, the importance of strong hydrogen bonding is shown. As the long-range structure in the alkyl and fluoroalkyl domains is dependent on the composition of the liquid, we propose that the heterogeneous, triphilic structure can be easily tuned by the molar ratio of the components. We believe that further development may allow the design of switchable, smart liquids that change their properties in a predictable way according to their composition or even their environment.
| S-EPMC4641458 | biostudies-literature
Project description:A series of clickable α-azide-ω-alkyne ionic liquid (IL) monomers with an ethylene oxide spacer were developed and applied to the synthesis of 1,2,3-triazolium-based poly(ionic liquid)s (TPILs) with high ionic conductivities via one-step thermal azide-alkyne cycloaddition click chemistry. Subsequently, the number of IL moieties in the resultant TPILs was further increased by N-alkylation of the 1,2,3-triazole-based backbones of the TPILs with a quarternizing reagent. This strategy affords the preparation of TPILs having either one or two 1,2,3-triazolium cations with bis(trifluoromethylsulfonyl)imide anions in a monomer unit. Synthesis of the TPILs was confirmed by 1H and 13C NMR spectroscopy and gel permeation chromatography. The effects of the length of the ethylene oxide spacer and the number of IL moieties in the IL monomer unit on the physicochemical properties of the TPILs were characterized by differential scanning calorimetry, thermogravimetric analysis, and impedance spectroscopy. The introduction of a longer ethylene oxide spacer or an increase in the number of IL moieties in the monomer unit resulted in TPILs with lower glass-transition temperatures and higher ionic conductivities. The highest ionic conductivity achieved in this study was 2.0 × 10-5 S cm-1 at 30 °C. These results suggest that the design of the IL monomer provides the resultant polymer with high chain flexibility and a high IL density, and so it is effective for preparing TPILs with high ionic conductivities.
| S-EPMC8153667 | biostudies-literature