Walking activity in a large cohort of boys with Duchenne muscular dystrophy.

ABSTRACT:

Introduction

In this study we explored walking activity in a large cohort of boys with Duchenne muscular dystrophy (DMD).

Methods

Step activity (monitored for 7 days), functional ability, and strength were quantified in ambulatory boys (5-12.9 years of age) with DMD and unaffected boys. Ambulatory status was determined 2 years later.

Results

Two to 5 days of activity monitoring predicted weekly step activity (adjusted R² = 0.80-0.95). Age comparisons revealed significant declines for step activity with increasing age, and relationships were found between step activity with both function and strength (P < .01). Our regression model predicted 36.5% of the variance in step activity. Those who were still ambulatory after 2 years demonstrated baseline step activ

SUBMITTER: Lott DJ 

PROVIDER: S-EPMC8314165 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature