A self-labeling protein based on the small ultra-red fluorescent protein, smURFP.
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ABSTRACT: Self-labeling proteins have revolutionized super-resolution and sensor imaging. Tags recognize a bioorthogonal substrate for covalent attachment. We show the small Ultra-Red Fluorescent Protein (smURFP) is a self-labeling protein. The substrate is fluorogenic, fluoresces when attached, and quenches fluorescent cargo. The smURFP-tag has novel properties for tool development.
SUBMITTER: Machado JH
PROVIDER: S-EPMC8341759 | biostudies-literature |
REPOSITORIES: biostudies-literature
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