Ontology highlight
ABSTRACT:
SUBMITTER: Betermier M
PROVIDER: S-EPMC85339 | biostudies-literature | 2000 Mar
REPOSITORIES: biostudies-literature
Molecular and cellular biology 20000301 5
Paramecium internal eliminated sequences (IESs) are short AT-rich DNA elements that are precisely eliminated from the germ line genome during development of the somatic macronucleus. They are flanked by one 5'-TA-3' dinucleotide on each side, a single copy of which remains at the donor site after excision. The timing of their excision was examined in synchronized conjugating cells by quantitative PCR. Significant amplification of the germ line genome was observed prior to IES excision, which sta ...[more]