Ontology highlight
ABSTRACT:
SUBMITTER: Samara M
PROVIDER: S-EPMC8628720 | biostudies-literature | 2021 Nov
REPOSITORIES: biostudies-literature
Samara Maria M Papathanassiou Maria M Farmakioti Ioanna I Anagnostou Maria M Satra Maria M Mitrakas Lampros L Anastasiou Dimitrios D Chasiotis Georgios G Christopoulos Agamemnon A Anagnostou Athanasios A Christodoulou Anastasios A Daponte Alexandros A Ioannou Maria M Koukoulis George G Tzortzis Vassilios V Vlachostergios Panagiotis J PJ
Current oncology (Toronto, Ont.) 20211115 6
The renin-angiotensin system (RAS), besides being a major regulator of blood pressure, is also involved in tumor angiogenesis. Emerging evidence suggests a correlation between the use of pharmacologic RAS inhibitors and a delay in urothelial bladder cancer (BC) progression. However, it is unknown whether RAS gene variants may predispose to the development of BC. This study examined the association of RAS single nucleotide polymorphisms (SNPs) including AT1R rs5186, AT2R rs11091046, REN rs1275083 ...[more]