Neurotoxins subvert the allosteric activation mechanism of SARM1 to induce neuronal loss.
Ontology highlight
ABSTRACT:
SUBMITTER: Wu T
PROVIDER: S-EPMC8638332 | biostudies-literature |
REPOSITORIES: biostudies-literature
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Project description:Continuous labelling HDX on WT ClpP and ClpP_extended, in apo and bortezomib-bound states.
Pulse labelling HDX on WT ClpP and ClpP_extended, 1, 30, 180 minutes post a 100X dilution, samples were subjected to D2O-based buffer for 10 s.
Folders for each experiment are organized per state, and time points. Peptide mapping and undeuterated controls are included.
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