Ontology highlight
ABSTRACT:
SUBMITTER: Popsuj S
PROVIDER: S-EPMC8719597 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Popsuj Sydney S Stolfi Alberto A
Frontiers in neuroscience 20211217
Conserved transcription factors termed "terminal selectors" regulate neuronal sub-type specification and differentiation through combinatorial transcriptional regulation of terminal differentiation genes. The unique combinations of terminal differentiation gene products in turn contribute to the functional identities of each neuron. One well-characterized terminal selector is COE (Collier/Olf/Ebf), which has been shown to activate cholinergic gene batteries in <i>C. elegans</i> motor neurons. Ho ...[more]