Metal-Free Trifluoromethylthiolation of Arylazo Sulfones.

ABSTRACT: A visible-light-driven protocol for the synthesis of aryl trifluoromethyl thioethers under photocatalyst- and metal-free conditions has been pursued. The procedure exploits the peculiar properties of arylazo sulfones (having electron-rich or electron-poor substituents on the (hetero)aromatic ring) as photochemical precursors of aryl radicals and S-trifluoromethyl arylsulfonothioates as easy-to-handle trifluoromethylthiolating agents.

SUBMITTER: Li A 

PROVIDER: S-EPMC8765700 | biostudies-literature |

REPOSITORIES: biostudies-literature