Ontology highlight
ABSTRACT:
SUBMITTER: Pozzi G
PROVIDER: S-EPMC88675 | biostudies-literature | 1999 Apr
REPOSITORIES: biostudies-literature
Pozzi G G Meloni M M Iona E E Orrù G G Thoresen O F OF Ricci M L ML Oggioni M R MR Fattorini L L Orefici G G
Journal of clinical microbiology 19990401 4
Mutations of rpoB associated with rifampin resistance were studied in 37 multidrug-resistant (MDR) clinical strains of Mycobacterium tuberculosis isolated in Italy. At least one mutated codon was found in each MDR strain. It was always a single-base substitution leading to an amino acid change. Nine different rpoB alleles, three of which had not been reported before, were found. The relative frequencies of specific mutations in this sample were different from those previously reported from diffe ...[more]