Ontology highlight
ABSTRACT:
SUBMITTER: Pao SC
PROVIDER: S-EPMC9029780 | biostudies-literature | 2022 Apr
REPOSITORIES: biostudies-literature
Pao Shih-Cheng SC Chu Mu-Tzu MT Hung Shuen-Iu SI
Pharmaceutics 20220415 4
Cancer immunotherapy has achieved multiple clinical benefits and has become an indispensable component of cancer treatment. Targeting tumor-specific antigens, also known as neoantigens, plays a crucial role in cancer immunotherapy. T cells of adaptive immunity that recognize neoantigens, but do not induce unwanted off-target effects, have demonstrated high efficacy and low side effects in cancer immunotherapy. Tumor neoantigens derived from accumulated genetic instability can be characterized us ...[more]