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A small change approach to prevent long-term weight gain in adults with overweight and obesity: a randomized controlled trial.


ABSTRACT:

Background

Efforts to manage obesity through weight loss are often unsuccessful as most adults are not able to sustain the major changes in behaviour that are required to maintain weight loss long term. We sought to determine whether small changes in physical activity and diet prevent weight gain in adults with overweight and obesity.

Methods

We randomized 320 sedentary adults with overweight or obesity to monitoring alone (MA, n = 160) or a small change approach (SCA, n = 160). In Phase I (2 yr), MA participants were asked to maintain their normal lifestyle and SCA participants were counselled to make small changes in diet and physical activity, namely a suggested increase in daily step count of 2000 steps with a decrease in energy intake of 100 kcal per day, with group and individual support. Phase II (1 yr) was a passive follow-up period. The difference in change in body weight between groups at 24 and 36 months from baseline was the primary outcome. Additional outcomes included waist circumference and cardiorespiratory fitness.

Results

Overall, 268 participants (83.8%) completed the 2-year intervention, and 239 (74.7%) returned at the end of the follow-up period at 3 years. The difference in body weight change between the SCA and MA groups was significant at 3, 6, 12 and 15 months from baseline, but was no longer significant at 24 months (mean change 0.9 [standard error (SE) 0.5] kg v. -0.4 [SE 0.5] kg; difference -0.6, 95% confidence interval [CI] -1.9 to 0.8) or at 36 months (-1.2 [SE 0.8] v. -0.7 [SE 0.8] kg; difference -0.5, 95% CI -2.2 to 1.2). Changes in waist circumference and cardiorespiratory fitness were not significantly different between groups at 24 or 36 months (both p > 0.1).

Interpretation

The SCA did not prevent weight gain compared with monitoring alone at 2 or 3 years in adults with overweight or obesity. On average, we observed prevention of weight gain in both arms of the trial.

Trial registration

ClinicalTrials.gov, no. NCT02027077.

SUBMITTER: Ross R 

PROVIDER: S-EPMC9053990 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature

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Publications

A small change approach to prevent long-term weight gain in adults with overweight and obesity: a randomized controlled trial.

Ross Robert R   Latimer-Cheung Amy E AE   Day Andrew G AG   Brennan Andrea M AM   Hill James O JO  

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20220301 9


<h4>Background</h4>Efforts to manage obesity through weight loss are often unsuccessful as most adults are not able to sustain the major changes in behaviour that are required to maintain weight loss long term. We sought to determine whether small changes in physical activity and diet prevent weight gain in adults with overweight and obesity.<h4>Methods</h4>We randomized 320 sedentary adults with overweight or obesity to monitoring alone (MA, <i>n</i> = 160) or a small change approach (SCA, <i>n  ...[more]

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