Nanoscopic insights into the surface conformation of neurotoxic amyloid β oligomers.
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ABSTRACT:
SUBMITTER: Banchelli M
PROVIDER: S-EPMC9054531 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Publications
Nanoscopic insights into the surface conformation of neurotoxic amyloid β oligomers.
Banchelli Martina M Cascella Roberta R D'Andrea Cristiano C Cabaj Leszek L Osticioli Iacopo I Ciofini Daniele D Li Mai Suan MS Skupień Krzysztof K de Angelis Marella M Siano Salvatore S Cecchi Cristina C Pini Roberto R La Penna Giovanni G Chiti Fabrizio F Matteini Paolo P
RSC advances 20200608 37
Raman spectroscopy assisted by localized plasmon resonances generating effective hot spots at the gaps between intertwined silver nanowires is herein adopted to unravel characteristic molecular motifs on the surface of Aβ<sub>42</sub> misfolded oligomers that are critical in driving intermolecular interactions in neurodegeneration. ...[more]
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