Ontology highlight
ABSTRACT:
SUBMITTER: Sakakida T
PROVIDER: S-EPMC9128179 | biostudies-literature | 2022 May
REPOSITORIES: biostudies-literature
Sakakida Tomoki T Ishikawa Takeshi T Doi Toshifumi T Morita Ryuichi R Endo Yuki Y Matsumura Shinya S Ota Takayuki T Yoshida Juichiro J Hirai Yasuko Y Mizushima Katsura K Higashimura Yasuki Y Inoue Ken K Okayama Tetsuya T Uchiyama Kazuhiko K Takagi Tomohisa T Abe Aya A Inoue Ryo R Itoh Yoshito Y Naito Yuji Y
Cancer science 20220317 5
Cancer cachexia and the associated skeletal muscle wasting are considered poor prognostic factors, although effective treatment has not yet been established. Recent studies have indicated that the pathogenesis of skeletal muscle loss may involve dysbiosis of the gut microbiota and the accompanying chronic inflammation or altered metabolism. In this study, we evaluated the possible effects of modifying the gut microenvironment with partially hydrolyzed guar gum (PHGG), a soluble dietary fiber, on ...[more]