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Co-registration of radiotherapy planning and recurrence scans with different imaging modalities in head and neck cancer.


ABSTRACT: MRI (magnetic resonance imaging) scans are frequently used in follow-up after radiotherapy for head and neck cancer. With the overall aim of enabling MRI-based pattern of failure analysis, this study evaluated the accuracy of recurrence MRI (rMRI) deformable co-registration with planning CT (computed tomography)-scans (pCT). Uncertainty of anatomical changes between pCT and rMRI was assessed by similarity metric analyses of co-registered image structures from 19 patients. Average mean distance to agreement and Dice similarity coefficient performed adequately. Our findings provide proof of concept for reliable co-registration of pCT and rMRI months to years apart for MRI-based pattern of failure analysis.

SUBMITTER: Kristensen MH 

PROVIDER: S-EPMC9284447 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature

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Co-registration of radiotherapy planning and recurrence scans with different imaging modalities in head and neck cancer.

Kristensen Morten Horsholt MH   Hansen Christian Rønn CR   Zukauskaite Ruta R   Johansen Jørgen J   Samsøe Eva E   Maare Christian C   Holm Anne Ivalu Sander AIS   Eriksen Jesper Grau JG  

Physics and imaging in radiation oncology 20220630


MRI (magnetic resonance imaging) scans are frequently used in follow-up after radiotherapy for head and neck cancer. With the overall aim of enabling MRI-based pattern of failure analysis, this study evaluated the accuracy of recurrence MRI (rMRI) deformable co-registration with planning CT (computed tomography)-scans (pCT). Uncertainty of anatomical changes between pCT and rMRI was assessed by similarity metric analyses of co-registered image structures from 19 patients. Average mean distance t  ...[more]

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