The Wnt/β-catenin signalling pathway in Haematological Neoplasms.
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ABSTRACT:
SUBMITTER: Yu S
PROVIDER: S-EPMC9558365 | biostudies-literature | 2022 Oct
REPOSITORIES: biostudies-literature
Publications
The Wnt/β-catenin signalling pathway in Haematological Neoplasms.
Yu Siwei S Han Ruyue R Gan Runliang R
Biomarker research 20221013 1
Leukaemia and lymphoma are common malignancies. The Wnt pathway is a complex network of proteins regulating cell proliferation and differentiation, as well as cancer development, and is divided into the Wnt/β-catenin signalling pathway (the canonical Wnt signalling pathway) and the noncanonical Wnt signalling pathway. The Wnt/β-catenin signalling pathway is highly conserved evolutionarily, and activation or inhibition of either of the pathways may lead to cancer development and progression. The ...[more]
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