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One-Pot High-throughput Synthesis of N3-Substituted 5-Arylidene-2-Thiohydantoin Amides and Acids

ABSTRACT: A one-pot high-throughput solid-phase method for the synthesis of N3-substituted 5-arylidene-2-thiohydantoin amide and acid has been developed. A tandem ring-closure and ring-open pathway is proposed as the mechanism of forming the two products.

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PROVIDER: S-EPMC9910623 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature

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