Ontology highlight
ABSTRACT:
SUBMITTER: Khachigian LM
PROVIDER: S-EPMC9942398 | biostudies-literature | 2023 Feb
REPOSITORIES: biostudies-literature
Journal of translational medicine 20230221 1
Neovascular age-related macular degeneration (nAMD) is a major cause of visual impairment and blindness. Anti-vascular endothelial growth factor (VEGF) agents, such as ranibizumab, bevacizumab, aflibercept, brolucizumab and faricimab have revolutionized the clinical management of nAMD. However, there remains an unmet clinical need for new and improved therapies for nAMD, since many patients do not respond optimally, may lose response over time or exhibit sub-optimal durability, impacting on real ...[more]